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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1939 1
1942 1
1943 1
1946 5
1947 2
1948 3
1950 2
1951 1
1952 2
1953 4
1954 2
1955 1
1956 5
1958 4
1959 4
1960 4
1961 6
1962 5
1963 8
1964 14
1965 11
1966 16
1967 21
1968 22
1969 29
1970 27
1971 22
1972 25
1973 34
1974 66
1975 104
1976 98
1977 135
1978 165
1979 169
1980 168
1981 127
1982 171
1983 177
1984 211
1985 243
1986 221
1987 220
1988 230
1989 263
1990 304
1991 324
1992 370
1993 388
1994 458
1995 622
1996 688
1997 769
1998 864
1999 922
2000 1004
2001 1113
2002 1145
2003 1216
2004 1430
2005 1510
2006 1502
2007 1462
2008 1533
2009 1607
2010 1689
2011 1761
2012 1743
2013 1746
2014 1685
2015 1635
2016 1632
2017 1578
2018 1473
2019 1565
2020 1563
2021 1579
2022 1379
2023 1286
2024 458

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42,042 results

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Page 1
Genome control by SMC complexes.
Hoencamp C, Rowland BD. Hoencamp C, et al. Nat Rev Mol Cell Biol. 2023 Sep;24(9):633-650. doi: 10.1038/s41580-023-00609-8. Epub 2023 May 25. Nat Rev Mol Cell Biol. 2023. PMID: 37231112 Review.
Many cellular processes require large-scale rearrangements of chromatin structure. Structural maintenance of chromosomes (SMC) protein complexes are molecular machines that can provide structure to chromatin. ...These DNA-shaping abilities place SMC complexes at the heart …
Many cellular processes require large-scale rearrangements of chromatin structure. Structural maintenance of chromosomes (SMC) protei …
Chromosome structures.
Benbow RM. Benbow RM. Sci Prog. 1992;76(301-302 Pt 3-4):425-50. Sci Prog. 1992. PMID: 1364580 Review.
Centromeres, the regions that mediate attachment of a chromosome to a meiotic or mitotic spindle, and telomeres, the natural ends of chromosomes, are structures that ensure that the correct number of full length chromosomes are maintained during the cell c …
Centromeres, the regions that mediate attachment of a chromosome to a meiotic or mitotic spindle, and telomeres, the natural ends of …
Cell-cycle dynamics of chromosomal organization at single-cell resolution.
Nagano T, Lubling Y, Várnai C, Dudley C, Leung W, Baran Y, Mendelson Cohen N, Wingett S, Fraser P, Tanay A. Nagano T, et al. Nature. 2017 Jul 5;547(7661):61-67. doi: 10.1038/nature23001. Nature. 2017. PMID: 28682332 Free PMC article.
Chromosomes in proliferating metazoan cells undergo marked structural metamorphoses every cell cycle, alternating between highly condensed mitotic structures that facilitate chromosome segregation, and decondensed interphase structures that accommodate transc …
Chromosomes in proliferating metazoan cells undergo marked structural metamorphoses every cell cycle, alternating between high …
Chromosome Dynamics during Mitosis.
Hirano T. Hirano T. Cold Spring Harb Perspect Biol. 2015 Feb 26;7(6):a015792. doi: 10.1101/cshperspect.a015792. Cold Spring Harb Perspect Biol. 2015. PMID: 25722466 Free PMC article. Review.
The primary goal of mitosis is to partition duplicated chromosomes into daughter cells. Eukaryotic chromosomes are equipped with two distinct classes of intrinsic machineries, cohesin and condensins, that ensure their faithful segregation during mitosis. ...The prod …
The primary goal of mitosis is to partition duplicated chromosomes into daughter cells. Eukaryotic chromosomes are equipped wi …
Chromosome Dynamics in Response to DNA Damage.
Seeber A, Hauer MH, Gasser SM. Seeber A, et al. Annu Rev Genet. 2018 Nov 23;52:295-319. doi: 10.1146/annurev-genet-120417-031334. Epub 2018 Sep 12. Annu Rev Genet. 2018. PMID: 30208290 Review.
Changes in nucleosome packing, checkpoint kinase activation, the cell cycle, chromosomal tethers, and external forces acting on nuclei in response to external and internal stimuli can alter the basal mobility of DNA in interphase nuclei of yeast or mammalian cells. …
Changes in nucleosome packing, checkpoint kinase activation, the cell cycle, chromosomal tethers, and external forces acting o …
Cohesin and CTCF control the dynamics of chromosome folding.
Mach P, Kos PI, Zhan Y, Cramard J, Gaudin S, Tünnermann J, Marchi E, Eglinger J, Zuin J, Kryzhanovska M, Smallwood S, Gelman L, Roth G, Nora EP, Tiana G, Giorgetti L. Mach P, et al. Nat Genet. 2022 Dec;54(12):1907-1918. doi: 10.1038/s41588-022-01232-7. Epub 2022 Dec 5. Nat Genet. 2022. PMID: 36471076 Free PMC article.
Yet it is unknown how frequently such contacts occur, how long they last and how they depend on the dynamics of chromosome folding and loop extrusion activity of cohesin. By imaging chromosomal locations at high spatial and temporal resolution in living cells, we sh …
Yet it is unknown how frequently such contacts occur, how long they last and how they depend on the dynamics of chromosome folding an …
Condensin-Based Chromosome Organization from Bacteria to Vertebrates.
Hirano T. Hirano T. Cell. 2016 Feb 25;164(5):847-57. doi: 10.1016/j.cell.2016.01.033. Cell. 2016. PMID: 26919425 Free article. Review.
They display highly characteristic, rod-shaped structures with SMC (structural maintenance of chromosomes) ATPases as their core subunits and organize large-scale chromosome structure through active mechanisms. ...Studies of bacterial condensins provide deep insight …
They display highly characteristic, rod-shaped structures with SMC (structural maintenance of chromosomes) ATPases as their core subu …
Telomeres and chromosome instability.
Murnane JP. Murnane JP. DNA Repair (Amst). 2006 Sep 8;5(9-10):1082-92. doi: 10.1016/j.dnarep.2006.05.030. Epub 2006 Jun 19. DNA Repair (Amst). 2006. PMID: 16784900 Review.
The regions amplified by B/F/B cycles can then be transferred to other chromosomes, either through the formation of double-minute chromosomes that reintegrate at other sites, or through end-to-end fusions between chromosomes. ...Thus, the loss of a sin …
The regions amplified by B/F/B cycles can then be transferred to other chromosomes, either through the formation of double-min …
A Topology-Centric View on Mitotic Chromosome Architecture.
Piskadlo E, Oliveira RA. Piskadlo E, et al. Int J Mol Sci. 2017 Dec 18;18(12):2751. doi: 10.3390/ijms18122751. Int J Mol Sci. 2017. PMID: 29258269 Free PMC article. Review.
Although still controversial, topoisomerase II has also been proposed to directly contribute to chromosome compaction, possibly by promoting chromosome self-entanglements. ...Here, we review the current knowledge on topoisomerase II role specifically during mitosis, …
Although still controversial, topoisomerase II has also been proposed to directly contribute to chromosome compaction, possibly by pr …
Mitotic Chromosome Mechanics: How Cells Segregate Their Genome.
Batty P, Gerlich DW. Batty P, et al. Trends Cell Biol. 2019 Sep;29(9):717-726. doi: 10.1016/j.tcb.2019.05.007. Epub 2019 Jun 20. Trends Cell Biol. 2019. PMID: 31230958 Free article. Review.
Faithful mechanical transport during mitosis requires that chromosomes undergo extensive structural changes as the cell cycle progresses, resulting in the formation of compact, cylindrical bodies. Such structural changes encompass a range of different activities, in …
Faithful mechanical transport during mitosis requires that chromosomes undergo extensive structural changes as the cell cycle …
42,042 results
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